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A team of scientists has developed a new method for improving T-cell manufacture by focusing on the materials involved in this process. T cells play a key role in the body's immune response against pathogens. As a new class of therapeutic approaches, T cells are being harnessed to fight cancer, promising more precise, longer-lasting mitigation than traditional, chemical-based approaches.
A current bottleneck in these approaches and other Adoptive T-cell Therapies is the production of sufficient numbers of high-quality T cells. The new research uses a polymer mesh to activate the T cells, a critical step for their production. This approach simplifies processing compared to systems in use today.Image credit: Lance Kam/Columbia Engineering
